This is about a life changing fact to many of the people who seek to burn excess fat and get in to shape.
In our human body, there are two types of fat, brown fat and white fat. We all know that fats increase the risk of diabetes and heart disease. But all fat is not created equal. The best example is brown fat. Brown fat has lot of mitochondria, which are the power plants of body cells, than the white fats
Brown fat, also called brown adipose tissue, is a special type of body fat that is turned on (activated) when you get cold. Brown fat produces heat to help maintain your body temperature in cold conditions. These brown fat contains many more mitochondria than white fat does. Mitochondria are the “engines” in brown fat which burns calories to produce heat. So by the process of Thermogenesis, these brown fat cells generate heat in cold temperatures. Not only cold temperatures, these brown fat can be stimulated by chemical signals also.
Even though brown fat are this important, they are present in very small amounts in a human body. So scientists have long hypothesize and finding alternative pharmacological methods to activate the fat to improve metabolism.
For thermogenesis, it is discovered that beta2-adrenergic receptors (b2-AR) in brown fat cells are responsible for the stimulation.
It is not that far to use a drug which specifically activate the target to stimulate brown fat in humans. When it is done, patients with type 2 diabetes will start to determine if this approach can be useful to improve the metabolic control of the disease too.